Southampton’s Under-21 Premier League Cup Round of 16 clash with Huddersfield Town will take place on Monday 25th January.
The game against the Terriers will take place at St Mary’s, with a kick-off time of 7pm GMT.
Holders Saints reached the last 16 of the competition thanks to a 1-0 win against Chelsea at the Staplewood Campus on Monday night.
Huddersfield meanwhile beat Middlesbrough and Nottingham Forest to reach this stage.
As a result of this tie, Saints’ trip to Everton in the Barclays Under-21 Premier League – scheduled for the same evening – will be re-arranged.
Tickets for the game at St Mary's will be free of charge to supporters.